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Information × Registration Number 0209U001521, 0106U004304 , R & D reports Title Investigation of molecular mechanisms of inhibition of furin - the main activator of some bacterial toxins - using synthetic peptides and their derivatives popup.stage_title Head Radavski U.; Kibirev V., Registration Date 06-02-2009 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 Peptides containing arginine (or its mimetics) were synthesized as potential inhibitors for serine proteases furin and thrombin. The best inhibitors of thrombin were found to be compounds which had at N-termini a residue of fatty (lauric) acid. These findings open new possibilities for synthesis of potent inhibitors of the studied enzymes.5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close