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Information × Registration Number 0209U002622, 0106U003266 , R & D reports Title Functional state of immune system and characteristics of clinical course of rheumatoid arthritis in the patients with opportunistic viral infections popup.stage_title Head Grishyna O.I., Registration Date 27-02-2009 Organization State Establishment "Mechnikow institute of microbiology and immunology of the Ukrainian MSA" popup.description2 One hundred and fifty patients with active RA were studied, features of RA clinical course were found in patients with EBV infection signs markers. Cellular and humoral immunity condition and functional activity of Th1- and Th2-cells in patients with RA and EBV infection signs and its dynamics on cicloferon therapy were studied. INF- , INF- and interleikin-4 (IL-4) in synovial fluid in RA and OA patients and its dynamics on cicloferon therapy were examined. The method of prediction of efficiency cicloferon administration was developed in patients with rheumatoid arthritis by prognostic significant appropriateness dynamics of IL-4 and IFN-? ratio determination Product Description popup.authors popup.nrat_date 2020-04-02 Close