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Information × Registration Number 0209U006301, 0105U009079 , R & D reports Title Commensal bacteria of mucosal sites for prophylaxis and therapy of human nosocomial infectious diseases popup.stage_title Head Fabrі Zoltan Yozefovych, Boyko Nadiya Volodymyrivna,, Registration Date 03-02-2009 Organization Uzhgorod National University popup.description2 The screening among of commensal microflora representatives the most effective antagonists to the opportunistic pathogens isolated by us in the hospital and veterinary farms has been performed. On the germ free and gnotobiotic immunocompetent and immunodeficient mouse models the basic molecular cellular mechanisms of immunomodulating influence of implemented selected commensals on host mucosal immune response has been revealed. The profile of cytokines secreted by human DC after their time-dependent exposure to selected commensal bacteria was identified. The feasibility of using these selected commensals for prevention and treatment of nosocomial (hospital) infection has been substantiated. New mono-component and/or composite bacteriological preparations for medical and veterinary practice have been developed and proposed.5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close