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Information × Registration Number 0209U008705, 0108U006697 , R & D reports Title Magnetic bioceramics based on calcium phosphates. popup.stage_title Head Tkachenko Mikola Vasiliovich, Registration Date 08-12-2009 Organization Kharkov National University named after V.N. Karazin popup.description2 The purpose of the work is researches of composite calcium-phosphate ceramics with magnetic fillers of a different chemical composition in a biological environment of white laboratory rats on bioactivity and biocompatibility. Methods of research - the histological analysis. A comparative analysis of bioactivity and biocompatibility of glass ceramics in system CaO-SiO2-P2O5-Fe2O3, and heat-generating effect in alternate magnetic field was made. It is shown, that transformation of glass ceramics to a bone begins from occurrence on implant surface of calcium-phosphate layers with hydroxyapatite structure. In the developed materials, the bioactive matrix consists from hydroxyapatite, that promotes substantial increasing of their bioactive properties. Samples of the composite ceramics which components is hydroxyapatite Са5(РО4)3ОН (80-95 wt. %) and magnetic particles maghemite ?-Fe2O3, magnetite Fe3O4, ferrite (BaFe12O19) and (СaFe12O19) and manganite La0,6Sr0,3Mn1,1O3± ?, were tested on bioactivity in a biological environment of white laboratory rats. Histological researches of surrounding bone defects tissues have shown, that just after implantations the composite material is surrounded neogenic bone tissues, degradation of a red bone brain and also possible toxic action of magnetic components on surrounding living tissues not observed. All types of samples are biocompatible and have high bioactive properties. Product Description popup.authors Глушко В.І. Зиман З.З. Ольховик Л.П. Пяничук О.А. Сіренко А.Ф. Ткаченко М.В. Ткаченко М.М. popup.nrat_date 2020-04-02 Close