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Information × Registration Number 0209U010518, 0105U008874 , R & D reports Title The investigation of the epilepsy chronic limbic forms development on posttraumatic epilepsy and kindling with the aim of their therapeutic cessation and preventive treatment. popup.stage_title Head Shandra Alexey Antonovich, Registration Date 15-12-2009 Organization Odessa state medical university popup.description2 On the basis of the received results it is shown that formation of a chronic convulsive syndrome in the conditions of models pharmacological kindling and a posttraumatic epilepsy is characterised by proof character, accompanied by the expressed electrographic and behavioural changes which have various character at stages finished kindling and postkindling, and also a posttraumatic epilepsy. In these experiments it is shown that epileptogenic excitation threshold decreases significantly in case of traumatic brain damage that proved by picrotoxin kindling accelerated formation. In the conditions of the used chronic epilepsy models carbamazepine and valproic acid revealed their anticonvulsive effects. Product Description popup.authors Вастьянов Руслан Сергійович Волохова Галина Олександрівна Герасимович Емма В’ячеславівна Денисенко Оксана Вікторівна Кащенко Ольга Анатоліївна Копйова Надія Вікторівна Ляшенко Світлана Леонідівна Община Ніна Василівна Поспєлов Олексій Михайлович Савченко Михайло Васильович Шандра Олексій Антонович popup.nrat_date 2020-04-02 Close