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Information × Registration Number 0209U010540, 0107U001200 , R & D reports Title To define the structural changes in brain tissue and internal organs due to multiple organ failure syndrom in brain trauma patients popup.stage_title Head Thepkiy Leonard Petrovith; Shamaev Mikchail Ivanovich, Registration Date 15-12-2009 Organization SI "Institute of neurosurgery named after acad. A.P. Romodanov of Academy of Medical Sciences of Ukraine" popup.description2 The Object - a syndrome poliorgan insufficient (SOFA)patient with TВI. Material: 277 events are insulated TBI, sick from 15 before 75 years,men 83%,woman 17%. Died 90 patients. The Methods: clinic - neurological, instrumental, biochemical, bacteriological, morphological, statistical. The Purpose - an improvement result treatments sick with traumatic injury CNS and SOFA on the grounds of clinic - an pathophysiology of the breaches under this pathology and forecasting of its development. Novelty - a system development of the forecasting of the development PON with provision for clinic - a statistical forecasting and algorithm intensive terastump that has allowed to reduce frequency of the development SOFA and mortal under TBI. On base of the collations clinic-laboratory and structured SOFA under trauma brain injury (TBI) miscellaneous degree to gravity is installed, nature and frequency developments early syndrome system-inflammatory answer (SIRS) under TBI. Between syndrome system-inflammatory answer and SOFA it is installed determined dependency. The уarly SIRS - high- carryinging information factor to gravity TBI. Between degree of the manifestation of the breaches function CNS on SIRS and function internal organ it is revealled the expressed corelational dependency. The Particularity SOFA under TBI in that that she appears not only under scale coma Glasgow, but in greater measure as a result of damages CNS. The Morphological studies is installed that change interdependent with degree of gravity of the trauma and time of the approach to deaths. The рulmonary complications circulation of the blood frustration reveal itself under TBI and are a structured manifestations to sharp respiratory insufficiency. The Preventive maintenance SOFA under TBI includes: maintenance identical oxigeniks, geospeakers, fight with internal accumulation toxin, preventive maintenance and treatment of the edema of the brain ( use solution on base sorbitil - sorbilakt) of the preventive maintenance and treatments festering-inflammatory complications. Product Description popup.authors Андрєєв С.А. Гавриш Р.В. Дмитренко А.Б. Кєворков Г.А. Каменская О.І. Мінов С.В. Макарова Т.А. Малишева Т.А. Ткачік І.П. Чепкій Л.П. Черненко О.Г. Шамаєв М.І. Шевчук В.А. popup.nrat_date 2020-04-02 Close