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Information × Registration Number 0209U010552, 0105U008885 , R & D reports Title Morphofunctional peculiarities of reproductive system of experimental animals in some external influences. popup.stage_title Head Kholodkova Olena Leonidivna, Registration Date 15-12-2009 Organization Odessa state medical university popup.description2 Deseases of the morphofunctional state of reproductive system in mice caused by doxorubicin hydrochloride and sodium nitrite influence is observed. It is shown as decreasing of fertility index, prolongation of the estrous cycle, decreasing of functional activity of supraoptic and arcuat nuclei of hypothalamus in female. Mass of testicle, specific density of spermatogenic epithelium cells, especially spermatogonii, index of spermatogenesis are fallen on these conditions in male. Restoration of the morphofunctional state of the mice reproductive system after the correction these pathological states with mesenchimal progenitor cells takes place. It is shown as appreciable renewal of the mass of reproductive organs, fertility index, increasing of functional activity of supraoptic and arcuat nuclei of hypothalamus, index of spermatogenesis and restoration of the structural integrity of testis. Product Description popup.authors Вернідуб Ірина Вікторівна Гудіна Ірина Вікторівна Десятський Валерій Володимирович Кошельник Олена Леніанівна Нескоромна Наталія Олександрівна Ославська Тетяна Михайлівна Пихтєєв Дмитро Михайлович Попов Олександр Георгійович Слученко Олександр Миколайович Холодкова Олена Леонідівна Щербатюк Аліна Леонідівна popup.nrat_date 2020-04-02 Close