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Information × Registration Number 0209U010905, 0107U000908 , R & D reports Title Epidemiological study of the non tumour incidence and mortality among the adult population, suffered on Chernobyl accident, during the 1986-2007 years popup.stage_title Head Buzunov V., Доктор медичних наук Registration Date 29-12-2009 Organization State Institution "Research Center for Radiation Medicine of Academy of Medical Sciences of Ukraine" popup.description2 Object: the Chernobyl clean-up workers, evacuees, residents of radioactive contaminated areas, children, exposed "in-utero", database of the State Registry for the Chernobyl survivors of Ukraine (SRU) as well as Clinical-and-epidemiological Registry (CER), SI "Research Centre for Radiation Medicine, Academy of Medical Sciences of Ukraine". Aim: To determine for post-accident period the regularities, estimates and predicted changes of nontumour incidence and mortality among adult population suffered after the Chernobyl accident, with regard to radiation and nonradiation factors. Methods: epidemiological, medical-and-statistical, risk-analysis, modeling. Results: Based on the data of SRU, true growth of nontumour disease incidence and prevalence was observed in the Chernobyl clean-up workers. Digestive and circulatory diseases, diseases of nervous system and sense organs made the most contribution to incidence structure. Mortality among clean-up workers increased from 2.12 ‰ to 10.78 ‰, mainly at the account of circulatory diseases. True relative and excess relative risks for some forms of nontumour diseases and death from nontumor pathology were proved to be dependent on whole-body external dose and time since recovery operation works. With adult evacuees, a reliable rise in dynamics of nontumour incidence was recorded, with the highest level in 1998-2002; age-and-sex peculiarities of the development of some disease forms were specified. A significant increase of mortality rates was observed, with the highest level in 2003-2007; circulatory diseases dominated in mortality structure. Calculations of nontumour mortality risks, their excesses per dose unit revealed the association between dose (0.25-0.32 Gy) and mortality from circulatory, digestive and prostate diseases. In dynamics, an increase in nontumour incidence and mortality depending on age, sex and doses accumulated at the place of residence was recorded among inhabitants of contaminated areas. Within 1992-2007, in evacuees from 30-km zone (in childhood and adolescence), low rates of many diseases and reliable increase of some nosologic forms, dependence on sex, age and whole-body external dose were established on the data of CЕR. Over the period 1992-2007, characteristic features of nontumour disease development and risks with respect to age, radiation and nonradiation factors were investigated in cohorts of male clean-up workers 1986-1987 and adult at the time of the accident female evacuees. Higher percentage (57.1 %) of eye diseases was proved in children exposed "in-utero". Prediction models for remote health effects of radiation effects of radiation exposure were developed. Product Description popup.authors Бабенко Тетяна Федорівна Бузунов Володимир Опанасович Войчулене Юлія Сергіївна Домашевська Тетяна Євгенівна Краснікова Людмила Іванівна Пирогова Олена Якимівна Прикащикова Катерина Євгенівна Терещенко Віктор Михайлович Цуприков В'ячеслав Антонович popup.nrat_date 2020-04-02 Close