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Information × Registration Number 0210U000642, 0107U008583 , R & D reports Title Macrocyclic bioregulators: calixarene chemical design and mechanisms of influence in modelling systems popup.stage_title Head Vovk A., Registration Date 03-03-2010 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 For the first time, it is shown high potential of some phosphonate derivatives of calix[4]arene and thiacalix[4]arene as effective inhibitors of alkaline phosphatases, nucleotide pyrophosphatase phosphodiesterase 1 and glutathione-S-transferase. On the basis of computer calculations by a method of molecular docking the mechanisms of complexation of functionalized calix[4]arenes with alkaline phosphatases are elucidated. Product Description popup.authors Кононець Л.А. Міщенко І.М. Музичка О.В. Танчук В.Ю. popup.nrat_date 2020-04-02 Close