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Information × Registration Number 0210U000965, 0107U007190 , R & D reports Title To study the influence of perinatal hypoxia, as inductor of the brain state of readiness for convulsions, on the functional activity of presynaptic transporters and metabotropic receptors of gamma-aminobutyric acid popup.stage_title Head Himmelreich Nina Hermanovna, Registration Date 26-04-2010 Organization A.V.Palladin Institute of Biochemistry of National Academy of Sciences popup.description2 The object of research: a rat brain (cortex, hippocampus and thalamus). The main aim: to study the key processes of inhibitory neurotransmission for establishing long-term consequences induced by perinatal hypoxia-evoked seizures that underlie a development of epileptiform state. It was established that changes in functional activity of high specific transport systems of the inhibitory neurotransmitter could be a cause of deregulated excitability. It has been also shown a possibility to correct neuronal changes by intensification of brain energy metabolism. Product Description popup.authors Гіммельрейх Ніна Германівна Кудінова Лідія Іванівна Пархоменко Микола Тимофійович Позднякова Наталія Георгіївна Яценко Людмила Миколаївна popup.nrat_date 2020-04-02 Close