Total number
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Total number
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Number of local repositories
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0210U001585,
0108U010544
,
Aplication of colloid gold for raising of photodynamic therapy antitumor efficiency
Gamaleya Nikolay Fedorovych,
26-02-2010
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology
The composition has been developed on the basis of a photosensitizer haematoporphyrin connected with colloidal gold that was stabilized in polyvinylpyrrolidone. Spectrophotometric and fluorometric properties of the complex were studied. The complex deposition kinetics in both normal and tumor tissues was investigated using transplanted tumors models (sarcoma 180 and carcinoma Lewis). The photodynamic activity of the complex was studied on malignant cell cultures in vitro. The photodynamic antitumor activity of the complex was investigated in animals with sarcoma 180 and carcinoma Lewis.
Долинський Генадій Анатолійович
Лісняк Іван Олексійович
Мамчур Анатолій Анатолійович
Прокопенко Ігор Вікторович
Шишко Євгенія Денисівна
2020-04-02
Updated: 2025-12-07
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