Search academic texts

Information × Registration Number 0210U003590, 0107U008449 , R & D reports Title Study of properties and creation of nanomaterials on the basis of complexes of biomolecules with carbon nanotubes. popup.stage_title Head Kharkyanen Valeriy Mykolayovych, Registration Date 11-02-2010 Organization Institute of physics NASU popup.description2 The technology of a preparation of transparent solution of single wall carbon nanotubes selected with DNA have been developed. The DNA - single wall carbon nanotube complexes were obtained. It was revealed that DNA shows non-canonical conformation in these complexes, the cites of interactions were determined. New methods on the basis of SEIRA and SERS for registration and characterization of carbon nanotubes in complex with homonucleotides have been developed. It was shown that in the complex under study the poly-A and poly-C depends on pH solution, meanwhile the conformation of poly-A, adsorbed on the nanotube, is determined by the initial poly-A conformation. The energy of formation of stable complexes- adenine-nanotube, thymine-nanotubes was estimated with ab initio quantum-chemical methods. Energy of interaction was calculated in the 3.2-12.1 kcal/mol region and protonated forms have energy of interaction in 1.5-2 time more in comparison with non-protonated forms on the basis of 2 different methods. The interaction of nucleic acids with carbon nanotubes caused by - stacking that takes place between surface of carbon nanotube and DNA bases. Visualization of carbon nanotube bundles, isolated nanotubes by AFM, transmission and scanning microscopy has confirmed the validity of the method of preparation of the samples of the isolated nanotubes and formation of the stable poly A-nanotube complex. In the DNA-nanotube complex, the DNA could show both single strand and double strand conformation. DNA adsorption on carbon nanotube surface occurs by wrapping or linear extension with change of DNA conformation, the Van der Vaalce forces acts in this case. Product Description popup.authors Андреєв Євгеній Олександрович Барабаш Юрій Маркович Довбешко Галина Іванівна Фесенко Олена Мар'янівна Харкянен Валерій Миколайович popup.nrat_date 2020-04-02 Close