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Information × Registration Number 0210U005105, 0108U005964 , R & D reports Title Molecular mechanisms of interaction, transport and transformation of nanoparticles in biological systems as a basis for creation of targe delivery popup.stage_title Head Ulberg Zoja Rudolfovna, Registration Date 07-06-2010 Organization F.D. Ovcharenko Institute of biocolloidal Chemistry NAS of Ukraine popup.description2 It was shown the gold nanoparticle size and concentration significantly influence on its interaction with and accumulation by U937 tumor cells. Cell-particle interaction are defined with high kinetic and maximum linkage during 3-5 min. The confocal and transmission electron microscopy methods were used for visual confirmation of gold nanoparticles contact interaction and accumulation by the U937 cells. Concentration optimum of gold nanoparticles interaction with U937 cells is over the range of ~ (0,1 -1,0) ng metal/cell for the particles of all examined sizes. The most effective accumulation of gold nanoparticles by U937 cells were observed for the particles with average dimension ~ 30 nm. Product Description popup.authors Горчев Василь Федорович Грузіна Тамара Григорівна Дибкова Світлана Миколаївна Паніна Зоя Олександрівна Рєзніченко Людмила Сергіївна popup.nrat_date 2020-04-02 Close