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Information × Registration Number 0210U005477, 0108U000219 , R & D reports Title Revealing of bioregulatory stereotype of action of low-molecular weight compounds with use of Langmuir monolayers and computer chemistry methods popup.stage_title Head Mogilevich Sergiy E., Registration Date 15-12-2010 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 It was shown, that the rate of enzymatic cleavage of phospholipid of monolayer films of distearoylphosphatidylcholine by phospholipase A2 was influenced mainly by bioregulators, which are activators of adenylatecyclase and (or) inhibitors of phospholipid signalling system. The model of phos-pholipase A2 interaction with the surface of distearoylphosphatidylcholine monolayer was developed within the framework of NAMD program package. This model enables the study of phospholipase A2 in-teraction with lipid monolayer in nanosecond range. Product Description popup.authors І.В.Семенюта І.В.Тетко В.В.Ковалішин В.В.Прокопенко В.В.Холодович В.Ю.Танчук Л.Л.Чарочкіна Л.О.Метелиця О.М.Ляхов О.О.Поярков popup.nrat_date 2020-04-02 Close
R & D report
Head: Mogilevich Sergiy E.. Revealing of bioregulatory stereotype of action of low-molecular weight compounds with use of Langmuir monolayers and computer chemistry methods. (popup.stage: ). Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine. № 0210U005477
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Updated: 2026-03-20