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Information × Registration Number 0210U006798, 0104U010587 , R & D reports Title The complex treatment of breast cancer via the usage of new methods of surgical, hormonal and chemotherapy with using intraarterial influence of drugs. Clinical-morphological research popup.stage_title Head Bondar Grigorij Vasilijovich, Registration Date 17-12-2010 Organization Donetsk National Medical University after named Gorky popup.description2 OBJECT: 1719 patients with breast cancer.OBJECTIVE:to work out and to realized the complex programme for improve the treatment results of breast cancer via the usage of selective intra-arterial polychemotherapy (IAPChT), radial and hormonotherapy. To study pathomorphism of the pathological process in dynamic. RESULTS: combined and complex methods for the treatment patients with breast cancer via randomized research including neoadjuvant and adjuvant cours of selective, superselective and and endolymphatic chemotherapy wih or without different variants of radial therapy have been obtained improvement of treatment results for these patients. NOVELTY : for the first time optimal surgical approaches for catheterization of great breast arteries have been substantiated on big clinical data; the clinical classification of vessels branching types in internal mammary artery pool has been devised. The low toxicity of intra-arterial chemodrug introduction have been proved. Firstly it has been satisfied that selective IAPChT combined with radial treatment in initial-and-inoperable breast cancer patients has been supported not only subtotal tumorous parenchyma's destruction but decrease of cellular cataplasia degree and intensification of process of education and ripening for connective tissue, increase vascularization degree and optimization of population composition and functional adequacy of immunocompetent cell. FIELD OF APPLICATION: oncological foundations, oncological research institutes. EFFICIENCY: improvement of the treatment's nearest and long-term results of breast cancer. Product Description popup.authors Іщенко Роман Вікторович Бондар Григорій Василійович Сєдаков Ігор Євгенович Семікоз Наталія Григоровна Смірнов Володимир Миколайович Трухін Дмитро Валентинович Хілько Дмитро Анатолійович Хлопушин Євген Юрійович Шлопов Валерій Генадійович Яковець Юрій Іванович popup.nrat_date 2020-04-02 Close