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Information × Registration Number 0210U006807, 0107U001685 , R & D reports Title To study the peculiarities of the rise, course, epidemiology and pathogenic mechanisms of cerebrovascular demyelination and inflammatory disease of nervous system in the big industrial region taking into account extremal manufactural factors and to work up into its early diagnostics, first and second prophylaxis and medicosocial rehabilitation popup.stage_title Head Yevtushenko Stanislav Kostyantinovich, Registration Date 17-12-2010 Organization Donetsk National Medical University after named Gorky popup.description2 OBJECT. 497 patients with cerebrovascular demyelination and inflammatory disease of nervous system: 118 patients with disseminated sclerosis (DS), 160 magistral locomotive drivers, 99 patients with polyneuropathy, 95 - with critical atherosclerotic stenosis of carotid arteries, 25 young womenfolks with ischemic stroke. OBJECTIVE: to increase of early detection's quality for most widespread cerebrovascular demyelination and inflammatory disease of nervous system and polyneuropathy. To evaluate the influence of manufacturing stress and of brachiocephal arteries pathology for development on cerebrovascular pathology. To evaluate the influence of pathological crimpiness in extracranial vessels on elaboration and course of DS. RESULTS: the role of pathological crimpiness in magistral head arteries (MHA) had been researched for progress of DS. The influence of chronical manufacturing stress on cerebral blood flow and on cardiac activity had been determined. The efficacy of surgical treatment of carotid's critical stenosis and value of transcranial magnetic stimulation for diagnostics and treatment of motor neuron pathology have been defined. The role of tableted forms of B group's vitamines have been evaluated for polyneuropathy and rebife efficacy - for DS treatment. NOVELTY: the meaning of open oval window on cardioembolic stroke forming had been established. The frequency of cerebral complications of carotid endarterioectomy had been detected. The mechanism of chronical manufacturing stress influence on formation of arterial hypertension, endothelial disturbances of cerebral blood flowdysfunction have been fixed. The biochemical and instrumental markers have been defined for evaluation and control of condition of patients with carotid's critical stenosis. The significance of determination of thickness of intima-media complex had been defined for locomotive drivers. FIELD OF APPLICATION: neurologic departments, sanatorium-and-spa institutions, maintenance inspection. Product Description popup.authors Євтушенко Станіслав Костянтинович Гончарова Яна Анатоліївна Грищенко Алла Борисівна Дюба Дінара Шамильєвна Луцький Ігор Степанович Симонян Вазген Ашотович. popup.nrat_date 2020-04-02 Close