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Information × Registration Number 0210U007106, 0105U007246 , R & D reports Title The investigation of reactions of N-substituted p-quinoneimines with arylsulfinic acids. popup.stage_title Head Avdeenko Anatolij P., Кандидат хімічних наук Registration Date 09-09-2010 Organization Donbass State Engineering Academy popup.description2 Object of research: the directions of addition reaction of arylsulfinate-anion to N-substituted-2,3(2,5)-dialkyl-1,4-benzoquinoneimines. Research purpose: carrying out of reactions of N-substituted-2,3(2,5)-dialkyl-1,4-benzoquinoneimines with sodium аrylsulfinates. The determination of structure of reaction products by IR-, NMR 1H, 13C spectroscopy and X-ray. The investigation of reaction mechanism. Research methods: organic synthesis, elemental analysis, IR, NMR 1H and 13C spectroscopy and X-ray analysis. Theoretical and practical results: As result of carried out investigation the common rules of reaction of N-substituted-2,6(3,5)-dialkyl-1,4-benzoquinoneimines with sodium аrylsulfinates have been found. It has been synthesized more 30 new compounds, which are potential biological compounds and can be used as medical drugs. The results of this work can be used for synthesis of new derivatives of p-quinoneimines with substituent ArSO2- in quinoid ring. Also the preparative chemistry of quinoneimines has been enriched. Novelty: For the first time it has been found the addition of sodium аrylsulfinates to N-substituted-2(3)-methyl(arylsulfonylamido)-1,4-benzoquinoneimines critically depends on redox potential of the latter: as a rule the N-arylsulfonylderivatives give the 1,4-addition products, N-[N-(arylsulfonyl)benzimidoyl]derivatives - the 1,4- and 1,6-addition products, but N-aroylderivatives - products of 1,4-, 1,6- and 6,1-addition. First it has been found the reaction ability of N-[N-(arylsulfonyl)benzimidoyl]-1,4-benzoquinoneimines are like both N-arylsulfonyl- and N-aroyl-1,4-benzoquinoneimines. The absence of addition products of arylsulfinate-anion to nitrogen atom depends on big size of group C(Ph)NSO2Ar. Efficiency of introduction: The synthesized compounds can be used in synthetic organic chemistry for the synthesis of new derivatives of p-quinoneimines and also for production of new perspective medical drugs. Area of application: For fundamental and special courses in organic chemistry for classical universities. Product Description popup.authors Євграфова Наталія Іванівна Авдєєнко Анатолій Петрович Васильєва Вікторія Михайлівна Глиняна Наталія Михайлівна Гончарова Світлана Анатоліївна Коновалова Світлана Олексіївна Лєдєньова Оксана Петрівна Лудченко Оксана Миколаївна Марченко Інна Леонідівна Менафова Юлія Валентинівна Михайличенко Оксана Миколаївна Романьков Дмитро Анатолійович Санталова Ганна Олександрівна Сергєєва Олександра Геннадіївна Юсіна Ганна Леонідівна popup.nrat_date 2020-04-02 Close