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Information × Registration Number 0210U007147, 0107U001355 , R & D reports Title Biorhythms of population composition and level of the metabolic systems of cellular link of innate immunity of habitants of the Zaporozhzhy industrial region. popup.stage_title Head Kolesnik Nadezhda Vasilyevna, Registration Date 16-09-2010 Organization Zaporozhye National University popup.description2 A subject of inquiry: 347 inhabitants Zaporozhye. A material of research: peripheric blood, a leukogram, activity myeloperoxidase, acidic and an alkaline phosphatase and cationic protein of neutrophils, acidic phosphatase of lymphocytes conform cuttings :МPОn, AcPn. APn. КБн, AcPlph The object of exploring: presence and parameters of annual biorhythm of metabolic systems of a cellular link of congenital immunodefence at person at ecologically hazardous environmental conditions, with the purpose of an estimation of their state and the functional reserve at the population of the Zaporozhye industrial district. Research techniques: the unified methods of determining of the quantitative compound of a leukogram, cytochemical methods of determining of activity :МPОn, AcPn. APn. КБн, AcPlph bloods; a statistical data handling in which on a state of explored indexes detection of effect of seasons requires a population chronobiology analysis. Theoretical result: Presence of seasonal rhythm of explored reading is erected, singularities of their parameters are characterized. Obtained data confirm conception about a that the biological time of the person naturally differs from a biological time of the person in anthropogenic man-made disasters that in case of the former the rhythmical system of the person functions as the resonator of undular processes, and in second - as their oscillator; thus the distribution of modes of frequency of oscillations in case of the former and in second noticeably to discriminate from each other. Practical result: Parameters of annual dynamics of modifications of explored reading are characterized: mezor, a standing of a minimum, a maximum, a vibration amplitude, independence of their intracellular regulation. Сhronobiology research of the quantitative composition of immunocompetent cells and states of metabolic systems of neutrophils as principal effector cells of immune system research first. Effectiveness of a heading: in educational process - 1 master's thesis is fulfilled, 12 degree operations, 12 course operations are protected. In special course of " The basis of clinical biological chemistry ", " Methods of a laboratory (clinical) immunology, "The molecular mechanisms hormonal and cytokinins regulations " lecture " Singularities of seasonal rhythm of metabolic systems in conditions of an anthropogenic load " is introduced. Сonditions of use: biology, medicine. Product Description popup.authors Качанова Жанна Сергіївна Колісник Надія Василівна Новосад Наталія Василівна Яловенко Аліна Сергіївна popup.nrat_date 2020-04-02 Close