Search academic texts

Information × Registration Number 0211U001091, 0108U001004 , R & D reports Title Investigation of free and immobilized oxidoreductases and hydrolases physico-chemical features in oxidative reactions of phenols, aromatic amines, hydrolysis and sythesis of 1,4-benzdiazepine-2-ones esters popup.stage_title Head Romanovskaya I., Доктор біологічних наук Registration Date 18-01-2011 Organization A.V.Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine popup.description2 Objects of іnvestigation - redox enzymes and enzymatic preparation : peroxidase, tyrosinase, and pig liver microsomal fraction carboxylesterase, phenolic compounds, aniline, 1,4-benzodiazepine-2-one esters. The aim of the development of enzymatic methods for oxidation of phenols, aromatic amines, as well as the hydrolysis and synthesis of 1,4-benzodiazepine-2-one esters, using the peroxidase and tyrosinase of plant and fungal origin, and pig liver microsomal fraction carboxylesterase immobilized on a modified natural and synthetic polymer supports; investigation physico-chemical features of their function as biocatalysts in aqueous and aqueous-organic media and the indastrtrial waster. Practical results - based on immobilized isolated redox enzymes and enzyme preparations, immobilized on polymeric carriers of natural and synthetic origin, developed highly active reusable biocatalysts for the oxidation of phenols and aromatic amines and the preparation of derivatives of 1,4-benzodiazepine-2-one derivatives with more pronounced pharmacological properties. Product Description popup.authors І. І. Романовська В.Є. Осетров Е.А. Шестеренко Н.О.Іллюшко О.В. Севастьянов С.С. Декіна Т.В. Михайлова Ю.А. Шестеренко popup.nrat_date 2020-04-02 Close