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Information × Registration Number 0211U002270, 0108U000028 , R & D reports Title To work out of informing criteria of estimation of risk development and progress of arterial hypertension in patients with metabolic syndrome, taking into account gender features, adiponectin blood levels and insulin resistance and effective approaches to the combined medical treatment of these persons. popup.stage_title Head S. Koval, Registration Date 28-01-2011 Organization State organization "Therapy Institute named after L.T. Malaya of Ukrainian Academy of Medical Sciences" popup.description2 Clinical, haemodynamic and metabolic features of hypertension development in patients in metabolic syndrome with sex difference depending on the initial indexes of adiponectinemia was set. The heterogeneity of hypertension development in patients with metabolic syndrome is exposed. The patogenetic role of hypoadiponectinemia in metabolic syndrome development and hypertension was set, especially in women. The high comparable of antihypertensive efficiency of two combinations of protracted after 24th week's therapy was shown (ACE ingibitor perindopril in combination with thiazyd diuretic indapamid and high-selective beta-adrenoblocer with NO-activating action nebivolol and the ІІІ generation calcium antagonist- lercanidipin), their ability to positive effect on insulin resistance state and lipid levels, for certain to increase adiponectin levels. The patogenetic evidance recommendations in relation of the combined variants of therapy in patients with metabolic syndrome with sex difference depending on the initial levels of adiponectin was developed. Product Description popup.authors Герасименко Ж.М. Кондаков І.К. Лавренко Т.А. Милославський Д.К. Мисниченко О.В. Набережнов М.Ю. Снігурська І.О. Циганков О.І. Щенявська О.М. popup.nrat_date 2020-04-02 Close