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Information × Registration Number 0211U004246, 0110U000171 , R & D reports Title Epidemiological study and modelling of regularities of the development cardiovascular incidence and mortality in the Chernobyl accident survivors popup.stage_title Head Buzunov V., Доктор медичних наук Registration Date 02-02-2011 Organization Research Centre for Radiation Medicine popup.description2 Object: the Chernobyl clean-up workers, evacuated population, residents of contaminated areas, database of the State Registry for the Chernobyl survivors of Ukraine (SRU) as well as Clinical-and-epidemiological Registry (CER), SI "Research Centre for Radiation Medicine, Academy of Medical Sciences of Ukraine". Aim: To determine the dynamics of cardiovascular morbidity and mortality among clean-up workers, evacuees, residents of contaminated areas, with regard to radiation and non-radiation factors. Methods: Epidemiological, medical-and-statistical, modeling. Results. Based on the data of SRU, an increase of cardiovascular morbidity in cohorts of clean-up workers 1986-1987 and adult evacuees was revealed for post-accident period. Hypertension, vascular diseases (arteries, arterioles, capillaries, veins and lymphatic vessels), chronic ischemic heart disease and cerebrovascular diseases are predominant in cardiovascular morbidity structure. Increase in cardiovascular mortality rates was noted among the Chernobyl clean-up workers 1986-1987 and adult evacuees. Chronic ischemic heart disease complicated by angina and acute myocardial infarction; cerebrovascular diseases complicated by stroke, cerebral infarction, hypertensive encephalopathy; diseases of arteries, arterioles and capillaries complicated by artery atherosclerosis, embolism and thrombosis; hypertension dominated in cardiovascular mortality structure. An increased risk for cardiovascular disease was found, age-related features of its development were identified among residents of contaminated areas. According to CER data, for those evacuated in childhood and adolescence in persons evacuated chronic heart diseases, hypertension and heart diseases contributed mostly to cardiovascular morbidity. CER data were used to investigate the features of cardiovascular morbidity in cohorts of male clean-up workers 1986-1987 and adult at the time of the accident female evacuees, over the period 1992-2008. Estimation and prediction models for cardiovascular morbidity in post-accident period were developed. Product Description popup.authors Бабенко Тетяна Федірівна Бузунов Володимир Опанасович Войчулене Юлія Сергіївна Домашевська Тетяна Євгеніївна Краснікова Людмила Іванівна Пирогова Олена Якимівна Прикащикова Катерина Євгеніївна Цуприков Вячеслав Антонович popup.nrat_date 2020-04-02 Close