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Information × Registration Number 0211U004425, 0110U005770 , R & D reports Title Development of biotherapy drugs (biomolecules) by RNA-based technologies to correct molecular disorders found in tumor cells. popup.stage_title Head Chekhun Vasyl Fedorovych, Registration Date 04-02-2011 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 Expression of multidrug resistance associated genes (P-glycoprotein, glutathione-S-transferase and topoisomerase II) was studied in sensitive and resistant to antitumor drugs human breast cancer MCF-7 cells. It was shown that in doxorubicin-resistant MCF-7/Dox cells P-glycoprotein expression was elevated. Resistant to cisplatin MCF-7/CP cells showed elevated expression of glutathione-S-transferase and topoisomerase II. Product Description popup.authors Бездєнєжних Наталія Олександрівна Лісовський Ігор Леонідович Лук'янова Наталія Юріївна Поліщук Людмила Захарівна Русецька Наталія Віталіївна Стеблянко Тамара Ісаківна Чехун Василь Федорович Юрченко Ольга Василівна popup.nrat_date 2020-04-02 Close