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Information × Registration Number 0211U004607, 0110U000231 , R & D reports Title To reveal the pathogenetic pathways of diabetes mellitus in Chernnobyl NPP accident survivors rxposed to ionizing radiation in dose range of 0.25 to 7.1 Gy popup.stage_title Head Kovalenko Alexander Nikolaevich, Registration Date 10-02-2011 Organization Research Centre for Radiation Medicine popup.description2 High frequency rate of diabetes mellitus was revealed in cleanup staff of Chernobyl NPP over 25 years passed after the accident. It makes up 14.2% that is 2.5 times more the same index in persons evacuated and residents of contaminated territories. It was found that mean absolute increment of disease rate in cleanup staff had been 2.7 times higher the Ukrainian population. The diabetes mellitus frequency increased with age and higher increase was revealed in 51-55 years free of gender. The high prevalence of hypercholesterolemia was found in the Chernobyl accident victims. In comparison with evacuated persons and contaminated territories residents the cleanup staff suffering from diabetes mellitus had essential increase of cases with the disease severe course, which needed insulin therapy. In cleanup staff before they had fallen ill with diabetes mellitus there was observed the carbohydrate metabolism disorders with serum glucose high level. In 1/7 part of these patients abnormalities of lipids metabolism was found and 4/5 part of patients was overweight. According to influence rate on diabetes mellitus incidence all risk factors could be distributed as following: male gender, body mass index, systolic blood pressure, glucose level, patient's age and beta-lipoproteins level. Product Description popup.authors Афанасьєв Дмитро Євгенович Білий Давид Олександрович Камінський Олексій Валентинович Копилова Ольга Василівна Чикалова Ірина Григорівна popup.nrat_date 2020-04-02 Close