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Information × Registration Number 0211U004686, 0109U001356 , R & D reports Title Medical and biological aspects of application salicylates, N-acetylated amino acid, benzimidazoles and benzodiazepines. popup.stage_title Head Koreniyk Ivan Ivanovich, Registration Date 16-02-2011 Organization Taurida National V.I. Vernadsky University popup.description2 For the first time it is established, that anti-inflammatory activity acetylsalicylate of zinc essentially exceeds that of aspirin. For the first time it is proved, that N-atselirovannye amino acids show anti-inflammatory and psychotropic activity. And, among tested N- acidylated amino acids CONH-Val has the most expressed anti-inflammatory action. For the first time it is proved, that CONH-Аlа, CONH-Val and CONH-Gly render stress protect action. For the first time it is shown, that depending on a dose at bimetile can show tranquilizated, anxiolytic and sedative effects. It is not excluded, that it is bound to intervention of the given agent in an exchange of monoamines that causes its differentiated influences on activity noradren - and serotonergic brain systems. For the first time presence at benzimidazole, 1,5-benzodiazepina and their some derivative analgetic properties is shown. It is found out, that tested materials depending on a dose raise a pain threshold, exceeding activity of analginum. For the first time it is established, that analgetic action acetylsalicylate of zinc essentially exceeds that of aspirin. For the first time it is proved, that neurotropic effects salicylic and acetylsalicylic acids and their salts are same in the excitatory systems of mammals and mollusks. Product Description popup.authors Гамма Тетяна Вікторовна Замотайлов Андрій Антонович Катюшина Оксана Валерієвна Колотілова Оксана Іванівна Хусаінов Денис Рашидович Черетаєв Ігорь Володимирович popup.nrat_date 2020-04-02 Close