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Information × Registration Number 0211U004772, 0109U001339 , R & D reports Title Influence of ionizing and non-ionizing radiation and bioaktive substances ov the mechanisms of stability of the biological systems popup.stage_title Head Shkorbatov Y.G., Registration Date 18-02-2011 Organization Kharkov National University named after V.N. Karazin popup.description2 Experimental objects: lines and hybrids of Drosophila, seeds of agricultural plants, cells of human buccal epithelium. Experimental methods: study of differential activity of genes, frequency of mutations, viability, degree of polyteny in chromosomes of Drosophila, dynamics of mitotic cycle and frequency of mutations of plants, state of chromatin and membranes of human cells. Results: conformities to the law of forming of radioadaptive answer are shown in plants, influence of low doses of ionizing, ultrawideband pulsed, and polarized microwave radiation, magnetic field effects on the state of human chromatin in Artemia. The method of determination of activity of bioactive substances (BAS), based on the analysis of degree of polyteny of giant chromosomes of salivary glands of Drosophila, is developed. Influence of vitamin of B12 and caffeine on the degree of polyteny was studied. In a line of Drosophila, got from a radiation-polluted natural environment, the significant decrease of the degree of polyteny is shown. The mutagenic effect of red light, caffeine, metoprene, dioxidine, and heteropolynuclear substances on the mutation rate in Drosophila was studied. Among the patients with the multiple sclerosis is registered an increase of number of granules of heterochromatin. There is a connection between functional state of human organism and the state of chromatin after the visual work. Product Description popup.authors Баєва Т. Винокурова Л. Горенська О. Рарог М. Страшнюк В. Стрижельчик Н. Чешко В. Чешко Т. Шакіна Л. Шестопалова Н. popup.nrat_date 2020-04-02 Close