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Information × Registration Number 0211U005479, 0110U003453 , R & D reports Title Examination of the temporal turn off mechanisms of immune control genes of female's reproductive sphere tumours by interfering ribonucleic acids. popup.stage_title Head Zaporozhan Valery Nikolaevich, Registration Date 14-12-2011 Organization Odesa National Medical University popup.description2 There were studied the indices of quantative density and functional activity of dendritic cells in euthyreosis and disorders of thyreoid status amongst rats. There was found the dependence of the change of thyroid gland function and functional state of dendritic cells population in the experimental conditions. The study of the impact of high frequency microwaves (HFMW) on the experimental adenocarcinoma allows to establish that HFMW (15 min.) exposure caused the singinificant increase of the sizes of experimental tumours comparingly with the that animals not exposured ot HFMW. There was stated that the use dendritic cells primered with turboeffect transfection reagent R-0537/siRNA allows to decrease the size of experimental tumours by 27% in the group of rats with experimental hypothyreosis and by 15% in the group of rats with experimental hyperthyreosis. There was conducted the study of the dendritic cells markers CD1a+ and CD83 in the cervical smear amongst the patients with cervical intraepithelial neoplasiae. There was determined the significant decrease of the population of unmatured (CD1a+) and matured (CD83) dendritic cell. Also there was conducted the study of the dendritic cells population in the endometrium of the patients with hyperplastic processes. There was determined the high rate of porliferation of studying cells and their association with clasters of natural killers CD56+ and cytotoxic lymphocytes CD83 Product Description popup.authors Андронов Дмитро Юрійович Грушко В’ячеслав Володимирович Запорожан Валерій Миколайович Марічереда Валерія Геннадіївна Мещерякова Наталя Володимирівна Пономаренко Андрій Іванович Сторчило Ольга В’ячеславівна popup.nrat_date 2020-04-02 Close