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Information × Registration Number 0211U005964, 0111U007525 , R & D reports Title Molecular mechanisms of cell signalling in normal and pathological conditions: the focus on ion channels. popup.stage_title Head Krishtal Oleg Oleksandrovych, Registration Date 20-12-2011 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 Expression and functional properties of ionic channels/receptors in normal conditions have been investigated. The role of IP3 receptors of the inner nuclear membrane of CA1 pyramidal and cerebellar Purkinje neurons in nuclear Ca2+ signalling has been studied. Spatial organisation of the sarcoplasmic reticulum (SR) Ca2+ -release channels in renal vascular smooth muscle cells has been characterized. Interaction of miR-1 with Cav3.2 mRNA has been investigated. Role(s) of opioid and cannabinoid receptors in the regulation of ion channels involved in primary nociception (P2X and TRPV) have been shown. Product Description popup.authors popup.nrat_date 2020-04-02 Close