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Information × Registration Number 0211U006242, 0105U005556 , R & D reports Title The study of mechanisms of biological activity and development of the system of the complex evaluation of the modern enterosorbents popup.stage_title Head Nikolaev Volodymyr Grygorovych, Registration Date 02-03-2011 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 Investigation of physicochemical and biological properties of enterosorbents based on activated carbon adsorbent, organic and inorganic silicon compounds and dietary fiber showed significantly greater preference for carbon enterosorbents towards dyes of different chemical nature, soluble and protein-bound marker substances and metabolites, proteins with different molecular weights, including pancreatic enzymes, bacterial endotoxin, as well as a number of antiretroviral and lipid lowering drugs. Enterosorption does'n cause the suppression of antitumor activity of cisplatin and reduce its systemic toxic action, it also positively affects the biochemical parameters of rats with streptozotocin diabetes, provides the corrective influence on the development of endogenous intoxication in experimental acute pancreatitis, significantly reduced mortality in rats with acute renal failure and may be used as an alternative method dyslipidemia treatment due to its high efficiency, safety and ease of use. Based on obtained experimental data the guidelines "Preclinical Studying of Enterosorbents» (protocol number 9 session of the Scientific-Expert Council of the State Expert Centre MOH of Ukraine of 10.28.2010 p). were developed and approved This guide is very importante for complex standardized and preclinical testing for existing and future enterosorbents. Product Description popup.authors Бардахівська Квітослава Ігорівна Гуріна Наталія Михайлівна Корнеєва Людмила Миколаївна Масленний Віталій Миколайович Сарнацька Вероніка В'ячеславівна Сахно Лариса Олексіївна Сидоренко Олексій Сергійович Снєжкова Єлізавета Олександрівна Юшко Лариса Олексіївна popup.nrat_date 2020-04-02 Close