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Information × Registration Number 0211U006669, 0106U002170 , R & D reports Title To study the mechanism of regenerative processes by investigating structural and some metabolic indices of organism in experimental animals after placenta transplantation at atherosclerosis popup.stage_title Head Yurchenko Tatyana N., Registration Date 09-03-2011 Organization Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of the Ukraine popup.description2 Introduction of cryopreserved of placenta tissue resulted in a rapid normalization of lipid spectrum of cord blood of rabbits s and a renewal of structural and functional integrity of endothelium, which specifies to the fact that allogeneic cryopreserved placenta (AСP) has hypolipidemic and angiotrophic effects. Introduction of AСP stimulated the system of mononuclear phagocytes and activated the mechanism of leukocyte clearance of lipids from a vascular wall as well as neoangiogenesis in the wall of aorta and myocardium, promoting, mutually with leucocytes, to the acceleration of reversible development of atherosclerosis. At experimental inflammation the application of biologically active substances of placenta tissue allows the normalizing of a cellular response to the focus of inflammation and state of peripheral blood. It demonstrates a reliable suppression of neutrophilic and strengthening of macrophage and fibroblast response if compared with shorter terms of inflammation usual proceeding. Consequently anti-inflammatory effect of placental biologically active substances is manifested with the limitation of alterative and strengthening of reparative events. Product Description popup.authors Говоруха Т.П. Жулікова О.П. Ковальов О.С. Кондаков І.І. Марченко Л.М. Рєпін М.В. Строна В.І. Шарлай Т.М. Юрченко Т.М. popup.nrat_date 2020-04-02 Close