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Information × Registration Number 0211U006674, 0109U007758 , R & D reports Title Development and introduction into practice of tissue recovering technology of treatment for damaged cartilages popup.stage_title Head Grischenko Valentin Ivanovich, Registration Date 09-03-2011 Organization Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of the Ukraine popup.description2 The research object is compression degenerative damages of intervertebral disc, multipotent mesenchymal stromal cells (MSC). The research aim is to develop an adequate model of human compression intervertebral discs damage in rats, to study the recovery process of intervertebral disc defect with the introduction of MSC culture. The research methods are cultural one, light microscopy, computertomographical and histological analysis, surgical methods of work with laboratory animals. The results of the research work. An adequate model of intervertebral disc (ID) degenerative damage in rats, which repeats the compression mechanism of its development in humans, was worked out. Optimal tactic of MSC introducing into the zone of injury was worked out and the effectiveness of its use in this disease, which manifests itself not only in increase the height of the ID but the full restoration of its structure, was proved. Field of use - medicine. Product Description popup.authors Гончарук Олена Іванівна Мазур С.П. Петренко Ю.О. Філіппова Марія Сергіївна Юхта М.С. popup.nrat_date 2020-04-02 Close