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0211U006825,
0108U001293
,
Study of compounds with antimicrobial activity among synthetic derivative kumarines and them geteroanalogues for further application in development of new medications.
Kazmirchuk Victor Vladimirovich,
11-04-2011
The Mechnikov Research Institute of microbiology and immunology at Kharciv
The new synthetic derivatives of kumarins are synthesized and them geteroanaloges, conducted their primary microbiological skrining with the use of standard set of reviewer test-cultures of Staphylococcus aureus, Streptococcus spp., Proteus vulgaris, Pseudomonas aeruginosa, Bacillus cereus, Escherichia coli, Klebsiella spp. and mushrooms of sort of Candida. A wide spectrum and high levels of antymikrobnial activity is certain, selected in the process of primary skrininga, matters in relation to a museum and and clinical cultures of microorganisms - exciters of infectious and festering-inflammatory diseases. The slow forming of rezistents of cultures of gram-positive microorganisms and mushrooms of sort of C .albicans to the most active new synthetic derivatives of kumarinov and them geteroanalogov and their belonging is well-proven to the IV class of toxicness are low-toxic matters.
Євсюкова В.Ю.
Іванова І.М.
Андреєва І.Д.
Білоконь І.Ф.
Волянська Н.О.
Казмірчук В.В.
Мирошник Н.І.
Поволокіна І.В.
Радченко О.О.
Скрипник В.Д
Чумаченко О.О.
Шульга Н.М.
Щербак О.М.
Юдін І.П.
2020-04-02
Updated: 2025-12-07
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