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Information × Registration Number 0211U007617, 0108U005238 , R & D reports Title Signalling functions and mechanisms of action of N-atsiletanolamins on ion channels in heart cells. popup.stage_title Head Shuba Yaroslav M., Доктор біологічних наук Registration Date 21-07-2011 Organization International center of molecular physiology popup.description2 We compared effects of N-stearoylethanolamine (NSE) and N-oleoylethanolamine (OEA) and on phospholipids composition myogenic and fibroblasts-like cells in culture. It was shown that in normal cells NSE decrease percentage content of phosphatidylinositol (PI), phosphatidylserine (PS) and sphingomyeline (SM) - important mediators of cell signaling. Under the influence of ОЕА the level of SM decreases as well, but at the same time PI and PS levels come up. NAEs mixture decreases PS and PI levels in cells and causes phosphatidylcholine (PC) amount increase. Moreover NSE and NAEs mixture decrease the content of main mitochondria membrane lipid - diphosphatidylglycerol (DPG). ОЕА increases DPG amount. Product Description popup.authors Асмолкова В.С. Войтичук О.І. Соткіс Г.В. popup.nrat_date 2020-04-02 Close