Search academic texts

Information × Registration Number 0211U008258, 0110U004752 , R & D reports Title Effect of coumaric derivatives on the activity of proton-activated receptors popup.stage_title Head Maximyuk Oleksandr Petrovych, Registration Date 21-04-2011 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 We have found that 3-amidinocoumarins can be used for generation of novel type of potent ASIC antagonists. The most active substances we have, showed IC50 near 10 nM for ASIC1a channels. Our data indicate that such molecules can be used for development of novel drugs against ischemic brain damage in stroke therapy. Product Description popup.authors В.В.Хмиз О.П.Максимюк popup.nrat_date 2020-04-02 Close