Search academic texts

Information × Registration Number 0211U008270, 0110U004745 , R & D reports Title Investigation of the molecular mechanisms of the course of Alzheimer's disease at the molecular and cellular levels and their pharmacological correction popup.stage_title Head Kostyuk Olena Platonivna, Registration Date 21-04-2011 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 We studied the possible desorders during Alzheimer's disease (AD) - dysfunction of mitochondria and endoplasmic reticulum in hippocampal neurons. We have found that at AD the level of intracellular calcium in the cytoplasm of neurons significantly increases, that may occur both due to excessive entry of calcium from the extracellular environment (for example, by calcium channels), and due to its excessive release from mitochondria and endoplasmic reticulum. Product Description popup.authors Гамаюн Ігор Володимирович Король Сергій Васильович Король Тетяна Юріївна Костюк Олена Платонівна Романенко Сергій Вячеславович popup.nrat_date 2020-04-02 Close