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Information × Registration Number 0211U009533, 0111U008349 , R & D reports Title Functionalized NanoGold Intensifier of Intermolecular Interactions under Surface Plasmon Resonance Conditions popup.stage_title Head Boltovets Praskoviya Mykolayivna, Registration Date 27-12-2011 Organization Institute of Semiconductor Physics of NAS of Ukraine popup.description2 Object of the research are metal layers and metal nanopartickles modified by low-molecular compounds. The aim of the work is the search of the optimal approach to the modification of the metal nanoparticlesby low-molecular compounds. Simple method of the immobilization of biologically active molecules with many functional fragments by Cd ion selective binding of their thiogroups with carboxygroups at the surface of the modified layer of Au. Biofunctional properties of such surface architectures were studied by surface plasmon resonance methodat the example of the gluathione (GSH) immobilized at the surface of mixed (a:b from 1:100 to 1:700) thiol monolayers with terminal groups methyl/hydroxil (a) and carboxil (b) types. Investigation of the inteaction between Ag nanoparticlec and glutathione molecules carried out. Changes in the Ag absorbtion spectrum on the influence of the glutathione are demonstrates.The possibility of the interaction between modified Ag nanoparticles and GST protein is shown by SPR method. Method of the research - surface plasmon resonance. The volume of work on the stage is executed fully. Product Description popup.authors Кравченко Сергій Олександрович Снопок Борис Анатолійовиі popup.nrat_date 2020-04-02 Close