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Information × Registration Number 0211U013140, 0110U006122 , R & D reports Title Designing and efficiency reserch of the recombinant baculovirus vectors for gene and vaccinotherapies popup.stage_title Head Strokovskaya Lyudmila Ivanovna, Registration Date 28-12-2011 Organization Institute of Molecular Biology and Genetics popup.description2 Were constructed recombinant baculoviruses with the reporter gene of eGFP and genes of cytocins - IL2, IL12, IL21 and beta-interferon. The level of expression of IL2, IL12 and beta-interferon interleucins was detected in the optimized terms of transduction of mammalian cells of recombinant baculoviruses. We got the line of mouse fetal fibroblast. Effective transduction by baculoviruses of these cells was shown. Interferon beta, that is expressed by the transductive fetal fibroblastis was ingibited of mouse tumors melanoma proliferation at co-cultivation of melanoma and fibroblasts cells . Product Description popup.authors Анопрієнко О.В. Вагіна І.М. Гончарова Л.О. Зінченко В.А. Кіхно І.М. Морозова Л.М. Чащина Л.І. popup.nrat_date 2020-04-02 Close