Search academic texts

Information × Registration Number 0211U013344, 0111U007041 , R & D reports Title Synthesis and physicochemical characteristics of directed transport nanosystems for medical and biological applications popup.stage_title Head Storozhuk Lyudmyla Petrivna, к.х.н. Registration Date 23-12-2011 Organization Institute of Surface Chemistry of the National Academy of Sciences of Ukraine popup.description2 Technique for synthesis magnetically operated nanocomposites based on transition metals oxides (MeFe2O4, Me = Fe2+, Ni2+, Co2+) with biologically compatible coating (SiO2)x were developed and optimized. Tetraethoxysilane (TEOS) and sodium silicate were used as precursors for formation of SiO2 onto surface of magnetic component. Content of SiO2 in nanocomposite surface layer were adjusted from 0,1 to 1,0 g for 1,0 g of magnetic component. Using a variety of physicochemical methods was revealed interconnection between structure, composition and magnetic properties of nanocomposites. It was shown that values of specific magnetization at saturation for nanocomposites magnetic component/SiO2 with content of nonmagnetic phase 0,2 g per 1 g of magnetic is close to those for initial magnetic phase. Decreasing of specific magnetization at saturation of samples and nonlinear change of coercive force with increasing of silicon dioxide content has been revealed. Adsorption interaction of immunoglobulin (Ig) and DNA with surface layers of magnetically operated nanocomposites was investigated. It has been found that adsorption of Ig and DNA amounts to ~ 0,5 mg and 0,55-0,6 mg respectively per 100 mg of adsorbent. Revealed that take place complete desorption of Ig and DNA from surface of investigated nanocomposites. Product Description popup.authors Мудрак Іван Михайлович Хуторний Сергій Валерійович popup.nrat_date 2020-04-02 Close