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Information × Registration Number 0211U013358, 0110U006121 , R & D reports Title Generation and characterization of moloclonal antibodies to oncogenic, mutant forms of fibroblast growth factor receptor (FGFR3 ) for diagnostics and immunotherapy of tumors popup.stage_title Head Filonenko Valeriy Viktorovitch, Доктор біологічних наук Registration Date 26-12-2011 Organization Institute of Molecular Biology and Genetics of NASU popup.description2 cDNA of various forms of FGFR3 have been сloned in vectors pcDNA3 and pcDNA4/TO in frame with Myc-tahom. The efficiency of expression of recombinant receptor isoforms in the cells НEK293 transfected by relevant plasmids has been analyzed. In the established cell models using antibodies against the bacterial recombinant fragments receptor analogs conditions of "cell-based ELISA" have been worked out, namely using various systems of fixation of cells, with or without fixation, and using different types of secondary antibody -fluorestsentlylabaled and and HRP-conugated. Product Description popup.authors Горбенко Олена Миколаївна Гришкова Віталіна Сергіївна Кіямова Рамзія Галямівна Маланчук Оксана Миколаївна popup.nrat_date 2020-04-02 Close
R & D report
Generation and characterization of moloclonal antibodies to oncogenic, mutant forms of fibroblast growth factor receptor (FGFR3 ) for diagnostics and immunotherapy of tumors
Head: Filonenko Valeriy Viktorovitch. Generation and characterization of moloclonal antibodies to oncogenic, mutant forms of fibroblast growth factor receptor (FGFR3 ) for diagnostics and immunotherapy of tumors. (popup.stage: ). Institute of Molecular Biology and Genetics of NASU. № 0211U013358
1 documents found

Updated: 2026-03-22


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