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Information × Registration Number 0212U000364, 0111U001982 , R & D reports Title Organic compounds of trivalent atom of Nitrogen: N-alkoxyamino-N-pyridinium salts popup.stage_title Head Alexander V.Tsygankov, Registration Date 02-02-2012 Organization The State Flight Academy of Ukraine popup.description2 The object of research is N-chloro-N-alkoxyureas, N-chloro-N-alkoxycarbamates, N,N-dialkoxycarbamates, N,N-dialkoxyureas. The aim is to study alkoholysis of N-chloro-N-alkoxyureas and N-chloro-N-alkoxycarbamates by tret-alcohols and establishment of possibility of nucleophilic substitution at nitrogen atom, development of new methods of synthesis of hindered bulky N,N-dialkoxycarbamates and N,N-dialkoxyureas. Conclusions and novelty. Possibility of nucleophilic substitution is first set at the nitrogen in N-chloro-N-alkoxyureas and N-chloro-N-alkoxycarbamates under the action of tret-butanol, the methods of synthesis of hindered bulky N,N-dialkoxycarbamates, N,N-dialkoxyureas are developed. The structure of N-metoxy-N-tret-butilurea is set by X-ray data. Application of the results. Synthesis of new hindered bulky N,N-dialkoxycarbamates and N,N-dialkoxyureas potential chemical mutagens direct action. The developed synthetic methods and tools can be used in the synthesis of complex natural compounds and their analogues. Keywords: N-chloro-N-alkoxyureas, N-chloro-N-alkoxycarbamates, N,N-dialkoxycarbamates, N,N-dialkoxyureas, anomeric amides, nucleophilic substitution at nitrogen Product Description popup.authors Циганков О.В. Штамбург В.Г. popup.nrat_date 2020-04-02 Close