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Information × Registration Number 0212U001153, 0108U011198 , R & D reports Title To determine the peculiarities in the development of children, whose fathers were subject to radiation impact in their childhood and adolescence ouring to the Chernobyl disaster. popup.stage_title Head Korenev M., Registration Date 18-01-2012 Organization Ukrainian Research Institute of Children and Adolescents Health Care popup.description2 Research object: the health of descendants whose parents were evacuated from the town of Pripyat or were living in their childhood in radioactively contaminated regions after the Chernobyl disaster. Objective: substantiation of prophylactic medical examination principles for children, whose parents were subject to radiation in childhood and adolescence, based on studying the incidence and nature of variations in their health status. Methods: conventional clinical, immunologic, instrumental (ECG, PhCS, ultrasound investigation of the heart, abdominal cavity organs, and the thyroid gland), the family kindred and phenotype description. Theoretical and practical results. A significant incidence of perinatal period burdened course, high rates of pathological morbidity at different age periods, as well as deviations in the immune system indices were established in children born from parents evacuated from Pripyat or resettled from areas under the control. The most significant changes in physical development, morbidity and imunoresistance were revealed in offspring whose parents had been residing in the contaminated areas in 1986-1989. The highest incidence of abnormal course of the ontogeny early stages was found in children whose parents at the time of the accident were under seven years of age. The highest level of disharmonious physical development and morbidity in puberty was registered in children from families where the parents at the time of the accident were twelve years or older. Inherited predisposition to the main noncontagious diseases was revealed in 97.1% of children from families of the exposed parents. An algorithm for dispensary observation of children whose parents had been exposed to radiation in childhood was proposed in the study , and the scope of examination and indications for rehabilitation measures for children were also established. Novelty. A complex clinicoanamnestic, laboratory and instrumental examination of children whose parents had been exposed to radiation in childhood owing to the Chernobyl accident was carried out. There were defined groups of children who require an increased variety of prophylactic medical examination measures depending on the data of their parents radiation history. Efficiency. Implementation of dispensary supervision measures concerning descendants of irradiated parents will contribute to early diagnosing their pathologies and prevent impairment of their health, as well as reduce treatment and rehabilitation expenses. Fields of application: pediatrics, family medicine, psychiatry, gastroenterology, endocrinology, genetics. Product Description popup.authors Бориско Галина Олександрівна Дємєнкова Інна Геннадіївна Калмикова Наталія Вікторівна Кашіна-Ярмак Вікторія Леонідівна Ковальова Валентина Іванівна Коренєв Микола Михайлович Костенко Тетяна Олександрівна Костенко Тетяна Павлівна Костюріна Наталія Олександрівна Міхановська Наталія Генадіївна Мельник Олена Володимирівна Молєва Вікторія Ігорівна Сальнікова Владлена Вікторівна Співак Тетяна Василівна Тараненко Оксана Богданівна popup.nrat_date 2020-04-02 Close