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Information × Registration Number 0212U002179, 0109U001564 , R & D reports Title Study of rats' higher nervous activity sensitivity to non-radiation stress upon previous exposure to ionizing radiation. popup.stage_title Head Talko Victory, Registration Date 27-01-2012 Organization Research Centre for Radiation Medicine popup.description2 Object: higher nervous activity of white rats after exposure to stresses of non-radiation nature in exposed and non-exposed to ionizing radiation animals. Goal: To study changes in rats' higher nervous activity sensitivity to exposure to non-radiation stress after their exposure to ionizing radiation at non-lethal doses. Methods: behavioral (shuttle and Skinner chambers, open field, white-black chamber), statistics. It is shown that the animals show activation of conditioned behavior directly after foot-shock, which follows by its depression. Dependence of conditioned behavior indices upon stress duration was found to be nonlinear. ANOVA-regression analysis showed statistically significant interaction between pre-exposure to ionizing radiation and stressing, modifying effects of the later. Sensitivity of animals' higher nervous activity to non-radiation stress upon pre-exposure to ionizing radiation was found to be nonlinear: lack or insignificant reaction to stress (0.5 Gy), its increase (1.0 Gy), and decline with further increase of dose up to its absence (6.0 Gy). Product Description popup.authors Варецький В.В. Дмитрієва І.Р. Доценко Н.П. Манучехр Ватанха Пахольченко В.М. Ракочі О.Г. Талько В.В. Тубальцева І.І. Тукаленко Є.В. Шелковський М.В. popup.nrat_date 2020-04-02 Close