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Information × Registration Number 0212U002707, 0109U000171 , R & D reports Title To study features the morphogenesis of thoracic aortic aneurysms of different origin popup.stage_title Head Zakharova Valentina Petrivna, Registration Date 30-01-2012 Organization M.M.Amosov National Institute of Cardio-Vascular Surgery of the Academy of Medical Sciences of Ukraine popup.description2 Based on the findings of the study of etiological factors due to specific morphological changes in the aortic wall developed the concept of the pathogenesis of aortic aneurysms. It is shown that the development of aortic aneurysms has a value of the simultaneous impact of several etiopathogenetic factors which in combination can be mutually reinforcing. These genetic studies indicate polymorphism elastin genes and that the presence of adenine in the pairs adenine-adenine or guanine - adenine in the gene for elastin (16 exons) may be a risk factor for the aneurism formation. Based on data from the experimental study the action of diphtheria toxin in aortic wall obtained data on the toxic effect of xenobiotics to wall. Product Description popup.authors Захарова Валентина Петрівна Кравченко Іван Миколайович Кравченко Віталій Іванович Руденко Олена Володимирівна popup.nrat_date 2020-04-02 Close