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Information × Registration Number 0212U002909, 0107U002243 , R & D reports Title The investigations of tumor immunotherapy technology using original cancer vaccines, cytokines and adjuvants popup.stage_title Head Shlyakhovenko Volodymyr Oleksiyovych, Registration Date 29-02-2012 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 Original approaches to the construction of cancer vaccines (CV) and elevation of their efficacy have been developed: CV generation on the basis of protein extracts from model tumor cells resistant to cytostatics and adjuvants of bacterial origin; improvement of glycopeptide vaccine by the use of original adjuvants, nanocomposites at the conditions of contrasuppression and modified level of polyamines; the development of technology of construction of gene-modified cell CV expressing mouse beta-defensin-2 (mBD-2), and DNA vaccines that code tumor-associated antigen (Muc-1), mBD-2 as chemokine, and granulocytic-macrophagal colony stimulating factor (GM-CSF). Product Description popup.authors Євстратьєва Л.М. Вербиненко А.В. Воєйкова І.М. Глушко Н.В. Діденко Г.В. Дідківська Л.П. Журавель О.В. Караман О.М. Карнаушенко О.В. Коханівська Л.М. Кузьменко О.П. Лісовенко Г.С. Міліневська В.О. Мосієнко В.С. Погрібний П.В. Потебня Г.П. Русанова Л.І. Солдаткіна М.О. Танасієнко О.А. Федосова Н.І. Хмара В.А. Черемшенко Н.Л. Шестакова Т.С. Шпак Є.Г. Яніш Ю.В. popup.nrat_date 2020-04-02 Close