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Information × Registration Number 0212U004145, 0109U001634 , R & D reports Title Theoretical investigation of mass transport processes, complicated by chemical and biochemical interactions, in micro(nano) systems popup.stage_title Head Svir Irina Borisovna, Registration Date 30-01-2012 Organization Kharkiv National University of Radioelectronics popup.description2 The aim of this project is dual: first, it was intended to determine the influence of uncompensated Ohmic drop in an electrolyte solution on mass and charge transfer processes in electrochemical cells with microelectrodes; second, it was planned to delineate the mechanism of transport of biological molecules-effectors and vesicles within living cells. The object of the study is transport processes of small molecules and ions through diffusion and migration in chemical (electrochemical) and biological (living cell) systems. We investigated mathematical models describing diffusion and diffusion-migration mass transport in physicochemical and biological micro- and nanoscale systems under steady state and transient conditions. Research methods included analytical and numerical methods for the solution of problems of mathematical physics. The most important results obtained with respect to electrochemical problems include: 1) a new mathematical model for studying the effects of Ohmic resistance of the electrolyte and double layer capacitance on voltammetry in an electrochemical system with a disk microelectrode covered with an electroactive monolayer prone to electron hopping; 2) a novel numerical approach to the simulation of diffusional mass transfer in an electrochemical system with an array consisting of any number of recessed disk microelectrodes. With respect to biological problems the following results were obtained: 1) a new theory explaining protein diffusion on the surface of a spherical vesicle that leads to the creation of an actin filament required for directed propulsion of the vesicle inside the cell; 2) a numerical-analytical method for the solution of an inverse problem for the determination of the vesicle opening function from experimentally measured currents. All the obtained results have fundamental value for natural sciences such as physical chemistry and biology. Product Description popup.authors Клименко Олексій Вікторович Олійник Олександр Ігорович popup.nrat_date 2020-04-02 Close