Search academic texts

Information × Registration Number 0212U004621, 0110U002157 , R & D reports Title 3. Testing of the classification criteria for systemic sclerodermia popup.stage_title Head Nadashkevych Oleh Nykonovych, Registration Date 25-01-2012 Organization Danylo Halytsky Lviv National Medical University popup.description2 Clinical-laboratory and immunological investigation taht were conducted and dynamic monitoring of patients with systemic scleroderma allowed to assemble and test the set of diagnostic criteria for this disease: 1. anticentromere antibodies or anti-SCL-70 antibody (anticentromere antibody may be replaced by definition of megcapillars with capillaroscopy of nail), 2. seal skin trunk parallel to the face and limbs; 3. Raynaud's syndrome, 4. swelling or seal skin with bilateral involvement of fingers, 5.bowliked and (or) joint contractures of the fingers 6. telangiectasia; 7. dysphagia or reflux esophagitis, 8. bibazylyar pulmonary fibrosis 9. calcification. Systemic scleroderma diagnosed in the presence of three criteria. In the absence of anticentromere antibodies, anti-SCL-70 antibodies and the criteria under the number "two" wee could excluded mixed connective tissue disease. Created a set of diagnostic criteria for systemic scleroderma has a sensitivity and specificity of 100% and gives possibility to set reliable diagnosis on the earliest stages of the disease, and allow to be recommended for use in medical practice Product Description popup.authors Возняк Ірина Ярославівна Гаєвська Віра Юріївна Дасюк Тарас Євгенович Дашко Мар'яна Олегівна Кріль Ірина Йосипівна Надашкевич Олег Никонович Павлюст Людмила Павлівна Паращук Богдан Миронович Толстяк Ярослав Федорович Чоп'як Валентина Володимирівна popup.nrat_date 2020-04-02 Close