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Information × Registration Number 0212U004853, 0111U000379 , R & D reports Title Objectification of morphological verification of neoplasms grade by their definition cell subpopulation composition to key indications multifactorial morphofunctional analysis popup.stage_title Head Grabovoy Alexandr Nikolaevih, Registration Date 06-02-2012 Organization Ukrainian Research Institute of Oncology and Radiology popup.description2 Subject of investigation: neuroblastoma, epithelial neoplasm of large intestine. The aim of investigation: to conduct multiple-factor analysis of heterogeneity of tumor cellular structure on the basis of changing in sequence DNA-RNA-protein; to define the main subpopulations of tumor cells. Methods of investigation: general histological, histochemical, immunohistochemical, mathematical. Equipment: tissue processor, microtome, dosers, microscope, digital image fixing system, computer. Conducted investigations determined parameters on basis of which tumor's cells can be divided on morphofunctional types. Based on correlation in different morphofunctional types of tumor cells which have been investigated such cells can be divided on subgroups with the high credibility value. For the first time on the basis of objective criterions heterogeneity of neuroblastoma, epithelial neoplasm of large intestine was shown. These are the grounds for their features (malignancy) assessment. Investigation's usage: department of morbid anatomy of oncological clinics and other medical institutions. Product Description popup.authors Іващенко Леся Миколаївна Вретик Галіна Михайлівна Грабовий Олександр Миколайович Егорова Олена Миколаївна Зарецький Михайло Борисович Ковальова Жана Семенівна Онучак Ольга Андрієвна Судяков Валерій Станіславович Тарасова Тетяна Миколаївна Третяк Валентина Василієвна popup.nrat_date 2020-04-02 Close