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Information × Registration Number 0212U004858, 0111U000378 , R & D reports Title To develop new methods ot brachytherapy with the use of HDR in patients with locally advanced cervical cancer. popup.stage_title Head Ivankova Valentina Stepanovna, Доктор медичних наук Registration Date 06-02-2012 Organization Ukrainian Research Institute of Oncology and Radiology popup.description2 Research object - 36 patients with the natively widespread forms of cancer of neck of uterus (МП OF РШМ). Purpose of work - to promote efficiency of the united radial therapy (ППТ) of patients with the natively widespread cancer of neck of uterus (МП OF РШМ) by development of new methods of брахітерапії with the use of sources of high activity during realization of ППТ. Research methods and apparatus : clinical, laboratory, radiodiagnostic, dosimetric. Simulator of session of irradiation - "SimView" 3000 (Siemens, Germany), ТЕРАТРОН, АГАТ-ВУ (MDR), GУNE SOURCE (HDR), УЗ-апарат "Aloca" - FLEXUS, vehicle for магніто-резонансного research (МРТ) of "Маgnetom - Vision - Plus - System" (Siemens), universal dosimeter of PTW Freiburg "Unidose E". In research it is included 36 patients with МП of РШМ, that got ППТ and up-diffused on two basic and control groups. In I basic group entered 10 patients with МП of РШМ, which внутрішньопорожнинну брахітерапію (ВПБТ) conducted on the vehicle of Gyne Source high-energy dose of radiation (HDR) in the mode of valid for one occasion hearth dose (РОД) 5 Гр on т. And 2 times for a week to the total hearth dose (СОД) 30 - 35 Гр for 6 - 7 factions; II a basic group was laid down 12 patients with МП of РШМ, what ВПБТ conducted on the vehicle of Gyne Source in the mode of РОД 7 Гр on т. And 1 one time per a week, СОД = 28 - 35 Гр for 4 - 5 factions. A control group was presented 14 patients with МП of РШМ, what ВПБТ conducted on the vehicle of АГАТ-ВУ with middle power of dose of radiation (MDR) of РОД in т. And - 8 Гр of х 1 time on a 6 - 7 twenty-four hours, СОД = 40 - 48 Гр for 5 - 6 factions. Worked out algorithm of control of dose descriptions of streams of photons on high-energy vehicles and radio-biology examination of vehicle of radio-therapy of Gyne Source is given with the sources of Со60 of high activity. Certain stages and sequence of допроменевої preparation of patients with МП of РШМ to ВПБТ НDR on the vehicle of Gyne Source and worked out methods of ВПБТ НDR by the sources of Со60 of high activity for patients with МП of РШМ. Studied possibilities of objective estimation of review of natively widespread карцином of neck of uterus on цитотоксичну therapy in a dynamics from data of radiological methods of research which has a прогностичне value and enables timely correction of the medical programs, in the case of necessity. Conducted clinical approbation of methods of ВПБТ on the vehicle of Gyne Source with the sources of Со60 of high activity for patients with МП of РШМ. Got results it is testified to efficiency of the worked out modes of брахітерапії for patients with МП of РШМ and absence of excessive toxicness of the applied methods on condition of high-quality допроменевої preparation. CANCER OF NECK OF UTERUS, RADIAL THERAPY, CONTROLLED FROM DISTANCE RADIAL THERAPY,BRACYTHERAPY, IS UNITED, , RADIOMODIFIERS, BIOTHERAPY Product Description popup.authors Іванкова Валентина Степанівна Бакай Ольга Олексіївна Барановська Лідія Михайловна Підлубна Тетяна Георгіївна Скоморохова Тетяна Володимирівна Хруленко Тетяна Валерівна Шевченко Галина Миколаївна popup.nrat_date 2020-04-02 Close