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Information × Registration Number 0212U004950, 0109U001412 , R & D reports Title Regulation of free radical processes under response of living organisms to harmful environmental factors popup.stage_title Head Lushchak Volodymyr Ivanovych, Registration Date 09-02-2012 Organization Precarpathian university named after Vassyl Stefanyk popup.description2 Research object is the response of living organisms to harmful environmental factors. The aim of study was to identify common mechanisms to achieve a balance between harmful and beneficial effects of reactive oxygen species in biological systems. The used methods were biochemical, microbiological, physiological, and mathematical statistics. It was found that glucose and fructose at high concentrations demonstrated toxicity on yeast cells; the negative effect of fructose was more expressed. Type and concentration of carbohydrates in the diet influences the lifespan, level of store nutrients and antioxidant system of D. melanogaster. The results indicate the perspectives of use of yeast and fruit flies as models to study the molecular mechanisms of carbohydrate metabolism disturbances. It was found that the roseroot extracts exhibit adaptogenic and geroprotective effects on yeast and fruit flies. Further detailed study of mechanisms of R. rosea action forms the preconditions for obtaining of medical preparations with health- and longevity-promoting effects. The positive effect of nitropruside sodium on weakening of the negative impact of high concentrations of sodium chloride on important physiological and biochemical parameters of plants was revealed. It can serve as a basis for developing of pathways of plant protection from salinization. There were a number of changes in hematological and biochemical parameters in the blood and various tissues of C. auratus under exposure by pesticides and transition metal ions. This determines the perspectives of practical application of these parameters as potential markers of intoxication of aquatic ecosystem. Product Description popup.authors Байляк Марія Михайлівна Господарьов Дмитро Валерійович Гусак Віктор Васильович Емха Богдана Іванівна Кубрак Ольга Ігорівна Лущак Володимир Іванович Семчишин Галина Миколаївна popup.nrat_date 2020-04-02 Close