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Information × Registration Number 0212U005562, 0112U006872 , R & D reports Title Molecular nature of the point mutations induced by modified DNA bases: model quantum-chemical investigation popup.stage_title Head Brovarets' Ol'ha Oleksandrivna, Registration Date 13-12-2012 Organization Institute of Molecular Biology and Genetics of NASU popup.description2 As a result of the project for the first time novel physico-chemical models of induced by modified DNA bases (hypoxanthine, 5-bromouracile, 5-fluorouracile and 5-chlorouracile) transitions, that adequately explain the results of some molecular biolological experiments and the simplest structural mechanisms of their optimization have been elaborated and analyzed. Physico-chemical mechanisms of the induced point mutations, in particular incorporation and replication errors in DNA, based on the novel structural ideas in the area of the spontaneous point mutagenesis have been revealed and validated. Product Description popup.authors Броварець Ольга Олександрівна Говорун Дмитро Миколайович popup.nrat_date 2020-04-02 Close