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Information × Registration Number 0212U006862, 0109U009070 , R & D reports Title Thermodynamics of ligands complexation, which binds to the surface of DNA molecule popup.stage_title Head Evstigneev Maxim Pavlovich, Registration Date 25-07-2012 Organization Sevastopol National Technical University popup.description2 A method for calculation of configurational entropy of complexation with DNA of non-rigid ligands were obtained. The contribution of various components of the enthalpy and entropy nature in full Gibbs energy of complexation reactions of non-rigid ligands. Using the data of NMR spectroscopy performed complete structural, thermodynamic and energetic analysis of hetero-antibiotic topotecan with various aromatic BAC. The problem of one-dimensional self-assembly of non-cooperative non-valence type for a class of DNA-binding ligands. The analysis of the entropy factors of loss of degrees of freedom upon binding of ligands to the non-rigid polymeric DNA. Product Description popup.authors Барановский С.Ф. Евстигнеев В.П. Костюков В.В. Хомутова Н.М. popup.nrat_date 2020-04-02 Close